Advanced research and health services have undergone transformation over the years, and perhaps the biggest change has been the cost reduction in whole genome sequencing. This has paved way for many to choose data analysis and genome sequencing. Let us retrace the milestones of bioinformatics to understand how it presently impacts advanced research and health services.
Mapping of The Human Genome
Fifteen years ago, the US government initiated a program to map the human genome. However another scientist beat the efforts of the government by getting the breakthrough that everyone was looking for. When it was first introduced, it actually cost a few billions of dollars. However, with technological advances, the prices are now comparatively rock bottom and are now at a few thousands of dollars. This has permitted research programs to conduct the studies.
The Need For More Studies To Help Understand Disease
Only when more research is conducted with bioinformatic analysis will it be possible to understand all about gene variation and the need for intervening in diseases. There is a need to make low cost whole exome sequencing tests available to many stakeholders. Typically, the tests take a close look at protein-making segments which are considered as the reason for Disease.
One of the advantages of exome sequencing cost is the lesser time that is necessary for conducting tests. Probably the most important advantage is the ability to capture data from lesser rna seq. The advantage here is that because it only requires lesser percentage, it need not sift through voluminous data. In other words the tests will be a lot easier.
Procedures Followed In Collection of Samples
By relying on the services of a reputed company like Biochain total RNA and DNA sequencing, purification and gene expression analysis can be carried out on the products. The collection and storage process followed includes the following :
Once the study design comes in, it goes through the collection process. The collection process has five sub stages namely informed consent, collection protocol, specimen collection, collection procedures and collection/annotation. In this process in depth standardized protocol to collect bio specimens are narrated to the concerned individuals.
Depending on the required analysis a wide variety of specimen types are collected. Blood and blood fractions like red blood cells, serum, plasma, Buffy coat are collected. Tissues resulting from autopsy, transplantation and surgery are collected depending up on the medical purpose. Samples like urine and buccal cells or saliva are also collected.
The collection procedure will differ based on the specimen that has to be collected or with respect to specimen type and the intended analysis that has to be carried out. But irrespective of the collection methodology used all the procedures should be cautiously designed and noted for the future use.
After the collection process the specimen goes in for the storage process. This is nothing but the preserving of the collected specimen. The storage process has the two sub stages labeling and data records.