New Data Reveals the U.S. States Where Adolescents Face the Highest Risk of Major Depressive Episodes

A new analysis of national mental health data has revealed significant state-by-state differences in the prevalence of major depressive episodes among U.S. adolescents — with some states seeing rates more than 20% above the national average. The findings highlight growing concerns about youth mental health, disparities in access to care, and the social conditions shaping the emotional well-being of young people.

The study, conducted by Simmrin Law Group using federal data sourced from KFF Mental Health statistics between 2021 and 2023, assessed the average number of adolescents aged 10 to 19 who experienced a major depressive episode. Rates were calculated per 1,000 adolescents in each state to identify where young people face the greatest mental health risks.

Nevada Has the Highest Adolescent Depression Rate in the Country

Nevada topped the list as the state with the highest prevalence of adolescent major depressive episodes.
From 2021 to 2023, an average of 57,000 Nevada adolescents experienced a major depressive episode every year. When compared to the state’s average population of 395,861 adolescents, this equates to 144.0 cases per 1,000 adolescents21.7% higher than the national average of 118.3.

While Nevada’s numbers dipped slightly between 2022 and 2023, the sustained high rate raises concerns about ongoing pressures facing young people, including access to mental health care, socioeconomic stressors, and the state’s limited mental health infrastructure — an issue long documented in national health rankings.

Oregon and Arizona Also Report Significantly Elevated Rates

Following Nevada, Oregon recorded the second-highest rate at 139.0 cases per 1,000 adolescents, nearly 17.5% above the national average. The state reported an average of 71,000 adolescents facing major depressive episodes during the three-year period.

Arizona ranked third, with 136.1 cases per 1,000 adolescents and an annual average of 130,000 affected adolescents from 2021 to 2023. Both states showed an overall decline between 2021–2022 and 2022–2023, but rates remain significantly elevated.

These figures reflect broader patterns identified by national mental health organizations — including increases in reported sadness, anxiety, and suicidal ideation among youth. Contributing factors can include academic pressure, social isolation, digital media exposure, and barriers to treatment.

Maryland and Colorado Round Out the Top Five

Rounding out the top five highest-risk states were:

  • Maryland134.3 cases per 1,000 adolescents

  • Colorado134.2 cases per 1,000 adolescents

Both states exceed the national average by more than 13%. Each reported stable numbers over the three-year period, with both showing slight fluctuations between 2021–2022 and 2022–2023.

Other High-Risk States

The remaining states in the top ten include:

  1. New Mexico — 133.1 per 1,000

  2. Washington — 132.8 per 1,000

  3. Minnesota — 130.3 per 1,000

  4. New Hampshire — 127.9 per 1,000

  5. Idaho — 127.6 per 1,000

Each of these states maintains double-digit margins above the national average, reinforcing that adolescent depression is not confined to one region or demographic.

A Public Health Issue That Demands State-Level Strategies

A spokesperson for Simmrin Law Group emphasized that the findings reflect not only the emotional struggles of adolescents but also significant gaps in state-level resources and support systems.

“Adolescent depression is a serious and often under-recognized public health issue,” the spokesperson noted. “Local healthcare access, socioeconomic conditions, and community support all play critical roles in shaping mental health outcomes.”

Experts consistently point to several interventions that can make a measurable difference:

  • Earlier screening in schools and pediatric practices

  • Stronger integration of mental health services, especially in underserved areas

  • Expanding access to therapy, including telehealth options

  • Community-based programs offering safe spaces and support for teens

  • Public awareness campaigns that destigmatize seeking help

Where the Rates Are Lowest

At the opposite end of the spectrum, Hawaii reported the lowest prevalence of adolescent major depressive episodes at 98.8 cases per 1,000 adolescents — substantially below the national average.

While no single factor explains Hawaii’s comparatively low rate, previous research suggests that community cohesion, outdoor lifestyles, and cultural practices may offer some protective effects.

A Call for Nationwide Action

The findings underscore the urgent need for proactive mental health policies at both state and national levels. With adolescent depression rates remaining high — and in some states increasing — experts warn that early intervention is essential for preventing long-term health, academic, and social consequences.

The full dataset and methodology are publicly available and were sourced from KFF Mental Health Data covering 2021–2023.